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Sotos syndrome is characterized by high birth length, rapid bone growth, distinctive facial features, and possible verbal and motor delays. It may be the result of an autosomal dominant inheritance pattern and it is more common in males than females. Developmental deficits or specific learning problems may be present. Speech and language delays may occur, although reported cases vary from normal development to severe delays. Hoarse voice is not uncommon.
KEY WORDS: Sotos syndrome, genetic syndrome, cerebral gigantism
Submitted on December 2, 1994
Accepted on March 2, 1995
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